From PEDIATRICS Vol. 119 No. 1 January 2007, pp. e124-e130 doi:10.1542/peds.2006-1222)

This study looked at the effectiveness of Lactobacillus Reuteri in the treatment of  Infant Colic (108 live bacteria per day).  Infants receiving L reuteri showed a significant reduction in daily crying time by day 7, compared with infants treated with simethicone. On days 14, 21, and 28, crying times were significantly different between the 2 treatment groups. At the end of the study (day 28), the median crying time in the probiotic group was 51 minutes/day (range: 26–105 minutes/day), compared with 145 minutes/day (range: 70–191 minutes/day) in the simethicone group, with a difference of 94 minutes/day.  On day 28, 95% were responders in the probiotic group and 7% were responders in the simethicone group.

Are you using probiotics in infant colic?  Please relate your experience in the comments below.